Mesothelioma: Chemotherapy Protocols

Cisplatin + Pemetrexed

Cisplatin (CDDP)
Pemetrexed (Alimta)

Vogelzang, NJ et al. Phase III study of pemetrexed in combination with cisplatin versus cisplatin alone in patients with malignant pleural mesothelioma. J Clin Oncol 2003; 21:2636

Carboplatin + Pemetrexed

Carboplatin (Paraplatin)
Pemetrexed (Alimta)

Ceresoli GL et al. Phase II study of pemetrexed plus carboplatin in malignant pleural mesothelioma. J Clin Oncol 2006; 24:1443

Pemetrexed

Pemetrexed (Alimta)

Scagliotti GV et al. Phase II study of pemetrexed with and without folic acid and vitamin b12 as a first-line therapy in malignant pleural mesothelioma. J Clin Oncol 2003; 21:1556.

Jassem J et al. Phase III trial of pemetrexed plus best supportive care compared with best supportive care in previously treated patients with advanced malignant pleural mesothelioma. J Clin Oncol 2008; 26:1698

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